2971-2990
| Ras Farnesyltransferase: A New Therapeutic Target
Daniele M. Leonard
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2991-2993
| Synthesis, Anti-Human Immunodeficiency Virus and Anti-Hepatitis B Virus Activities of Novel Oxaselenolane Nucleosides
Jinfa Du,
Sergey Surzhykov,
Ju Sheng Lin,
M. Gary Newton,
Yung-Chi Cheng,
Raymond F. Schinazi, and
Chung K. Chu
[Full Article -
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2994-2996
| Fused Pyrrolo[2,3-c]carbazol-6-ones: Novel Immunostimulants That Enhance Human Interferon- Activity
Robert L. Hudkins,
James L. Diebold,
Thelma S. Angeles, and
Ernest Knight, Jr.
[Full Article -
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2997-3008
| Dihydrobenzofuran Analogues of Hallucinogens. 4.
Aaron P. Monte,
Steve R. Waldman,
Danuta Marona-Lewicka,
David B. Wainscott,
David L. Nelson,
Elaine Sanders-Bush, and
David E. Nichols
[Full Article -
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3009-3013
| Synthesis and Study of Thiocarbonate Derivatives of Choline as Potential Inhibitors of Acetylcholinesterase
Nicholas A. J. Boyle,
Vincenzo Talesa,
Elvio Giovannini,
Gabriella Rosi, and
Scott J. Norton
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3014-3024
| Medetomidine Analogs as  2-Adrenergic Ligands. 3. Synthesis and Biological Evaluation of a New Series of Medetomidine Analogs and Their Potential Binding Interactions with 2-Adrenoceptors Involving a "Methyl Pocket"
Xiaoyan Zhang,
Joseph E. De Los Angeles,
Mei-Ying He,
James T. Dalton,
Gamal Shams,
Longping Lei,
Popat N. Patil,
Dennis R. Feller,
Duane D. Miller, and
Fu-Lian Hsu
[Full Article -
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3025-3031
| Conformational Studies of RS-66271, an Analog of Parathyroid Hormone-Related Protein with Pronounced Bone Anabolic Activity
Maria Pellegrini,
Alessandro Bisello,
Michael Rosenblatt,
Michael Chorev, and
Dale F. Mierke
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3032-3039
| Conformationally Restricted Analogues of Trimethoprim: 2,6-Diamino-8-substituted Purines as Potential Dihydrofolate Reductase Inhibitors from Pneumocystis carinii and Toxoplasma gondii
Aleem Gangjee,
Anil Vasudevan, and
Sherry F. Queener
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3040-3048
| Nonclassical 2,4-Diamino-5-aryl-6-ethylpyrimidine Antifolates: Activity as Inhibitors of Dihydrofolate Reductase from Pneumocystis carinii and Toxoplasma gondii and as Antitumor Agents
Claire Robson,
Michelle A. Meek,
Jan-Dierk Grunwaldt,
Peter A. Lambert,
Sherry F. Queener,
Dirk Schmidt, and
Roger J. Griffin
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3049-3056
| Antitumor Agents. 178. Synthesis and Biological Evaluation of Substituted 2-Aryl-1,8-naphthyridin-4(1H)-ones as Antitumor Agents That Inhibit Tubulin Polymerization
Ke Chen,
Sheng-Chu Kuo,
Ming-Chieh Hsieh,
Anthony Mauger,
Chii M. Lin,
Ernest Hamel, and
Kuo-Hsiung Lee
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3057-3063
| Curcumin Analogs with Altered Potencies against HIV-1 Integrase as Probes for Biochemical Mechanisms of Drug Action
Abhijit Mazumder,
Nouri Neamati,
Sanjay Sunder,
Jutta Schulz,
Heinz Pertz,
Eckart Eich, and
Yves Pommier
[Full Article -
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3064-3070
| 7-Spirobenzocyclohexyl Derivatives of Naltrexone, Oxymorphone, and Hydromorphone as Selective Opioid Receptor Ligands
Xinqin Fang,
Dennis L. Larson, and
Philip S. Portoghese
[Full Article -
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3071-3076
| Structure-Activity Studies on Position 14 of Human -Calcitonin Gene-Related Peptide
Jianzhong Li,
James E. Matsuura,
David J. J. Waugh,
Thomas E. Adrian,
Peter W. Abel,
Mark C. Manning, and
D. David Smith
[Full Article -
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3077-3084
| Inhibition of Melanoma Cell Binding to Type IV Collagen by Analogs of Cell Adhesion Regulator
Janelle L. Lauer,
Leo T. Furcht, and
Gregg B. Fields
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3085-3090
| Molecular Modeling and 3D-QSAR Studies on the Interaction Mechanism of Tripeptidyl Thrombin Inhibitors with Human -Thrombin
Hualiang Jiang,
Kaixian Chen,
Yun Tang,
Jianzhong Chen,
Quan Li,
Qinmi Wang, and
Ruyun Ji
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3091-3099
| Synthesis and Structure-Activity Relationships of Potent Thrombin Inhibitors: Piperazides of 3-Amidinophenylalanine
Jörg Stürzebecher,
Dagmar Prasa,
Jörg Hauptmann,
Helmut Vieweg, and
Peter Wikström
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3100-3108
| Evolution of the Dmt-Tic Pharmacophore: N-Terminal Methylated Derivatives with Extraordinary  Opioid Antagonist Activity
Severo Salvadori,
Gianfranco Balboni,
Remo Guerrini,
Roberto Tomatis,
Clementina Bianchi,
Sharon D. Bryant,
Peter S. Cooper, and
Lawrence H. Lazarus
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3109-3118
| Synthesis and Binding Affinity of 2-Phenylimidazo[1,2-a]pyridine Derivatives for both Central and Peripheral Benzodiazepine Receptors. A New Series of High-Affinity and Selective Ligands for the Peripheral Type
Giuseppe Trapani,
Massimo Franco,
Laura Ricciardi,
Andrea Latrofa,
Giuseppe Genchi,
Enrico Sanna,
Francesca Tuveri,
Elisabetta Cagetti,
Giovanni Biggio, and
Gaetano Liso
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3119-3129
| Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate between Metabotropic Glutamate Receptor Subtypes
Francine C. Acher,
Frédérique J. Tellier,
Robert Azerad,
Isabelle N. Brabet,
Laurent Fagni, and
Jean-Philippe R. Pin
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3130-3139
| Alkyl-Substituted Amino Acid Amides and Analogous Di- and Triamines: New Non-Peptide G Protein Activators
Christian Leschke,
Rüdiger Storm,
Evelyn Breitweg-Lehmann,
Torsten Exner,
Bernd Nürnberg, and
Walter Schunack
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3140-3140
| Chemistry Today and Tomorrow: The Central, Useful, and Creactive Science By Ronald Breslow. American Chemical Society, Washington, DC. 1997. ix + 134 pp. 18 × 25.5 cm. ISBN 0-8412-34640-4. $19.95.
Manfred E. Wolff
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3140-3140
| Books of Interest
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